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Hesham M Korashy Selected Research

Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)

9/2022Lead Nitrate Induces Inflammation and Apoptosis in Rat Lungs Through the Activation of NF-κB and AhR Signaling Pathways.
6/2022Aryl Hydrocarbon Receptor Promotes Cell Growth, Stemness Like Characteristics, and Metastasis in Human Ovarian Cancer via Activation of PI3K/Akt, β-Catenin, and Epithelial to Mesenchymal Transition Pathways.
2/2022Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies.
1/2022Epigenetic Regulation of Cancer Stem Cells by the Aryl Hydrocarbon Receptor Pathway.
12/2021In vivo and in vitro studies evaluating the chemopreventive effect of metformin on the aryl hydrocarbon receptor-mediated breast carcinogenesis.
8/2021Influence of the Aryl Hydrocarbon Receptor Activating Environmental Pollutants on Autism Spectrum Disorder.
1/2017Erratum to: Aryl hydrocarbon receptor/cytochrome P450 1A1 pathway mediates breast cancer stem cells expansion through PTEN inhibition and β-Catenin and Akt activation.
1/2017Aryl hydrocarbon receptor/cytochrome P450 1A1 pathway mediates breast cancer stem cells expansion through PTEN inhibition and β-Catenin and Akt activation.
3/2016Ketoconazole Stereoisomers Differentially Induce Cytochrome P450 1A1 Between Human Hepatoma HepG2 and Mouse Hepatoma Hepa1c1c7 Cells.
4/2015Metformin inhibits 7,12-dimethylbenz[a]anthracene-induced breast carcinogenesis and adduct formation in human breast cells by inhibiting the cytochrome P4501A1/aryl hydrocarbon receptor signaling pathway.
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Hesham M Korashy Research Topics

Disease

16Neoplasms (Cancer)
06/2022 - 12/2007
12Hepatocellular Carcinoma (Hepatoma)
10/2019 - 09/2004
8Breast Neoplasms (Breast Cancer)
12/2021 - 05/2013
7Inflammation (Inflammations)
09/2022 - 02/2015
7Cardiotoxicity
06/2022 - 01/2012
4Pneumonia (Pneumonitis)
09/2022 - 02/2015
4Cardiovascular Diseases (Cardiovascular Disease)
01/2021 - 01/2006
4Heart Failure
01/2021 - 04/2013
3Hyperglycemia
03/2022 - 07/2011
3Carcinogenesis
01/2022 - 04/2015
3Hypertension (High Blood Pressure)
01/2021 - 01/2014
3Obesity
01/2021 - 04/2019
3Hypertrophy
01/2020 - 04/2013
3Insulin Resistance
04/2019 - 03/2015
3Cardiomegaly (Heart Hypertrophy)
03/2014 - 01/2012
2BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
06/2022 - 01/2014
2Vascular Remodeling
03/2022 - 01/2020
2Heart Diseases (Heart Disease)
01/2021 - 01/2012
2Lung Neoplasms (Lung Cancer)
03/2020 - 11/2018
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2020 - 01/2014
2Acute Lung Injury
05/2016 - 02/2015
2Diabetic Nephropathies (Diabetic Nephropathy)
03/2015 - 07/2011
1Ovarian Neoplasms (Ovarian Cancer)
06/2022
1Neoplasm Metastasis (Metastasis)
06/2022
1Myeloid Leukemia (Leukemia, Myelocytic)
06/2022
1Diabetes Mellitus
03/2022
1Melanoma (Melanoma, Malignant)
02/2022
1Autism Spectrum Disorder
08/2021
1Leukemia
01/2020
1Cardiovascular Abnormalities
01/2020
1Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy)
01/2020
1Lymphoma (Lymphomas)
01/2020
1Stroke (Strokes)
08/2019
1Cerebral Hemorrhage
08/2019
1Ischemic Stroke
08/2019

Drug/Important Bio-Agent (IBA)

19Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA
09/2022 - 09/2004
14Cytochrome P-450 CYP1A1 (CYP1A1)IBA
12/2021 - 09/2004
12Proteins (Proteins, Gene)FDA Link
09/2022 - 05/2007
12Cytochrome P-450 Enzyme System (Cytochrome P450)IBA
01/2017 - 04/2004
11Messenger RNA (mRNA)IBA
01/2020 - 05/2007
8EnzymesIBA
11/2016 - 04/2004
7Tyrosine Kinase InhibitorsIBA
06/2022 - 05/2013
5Pharmaceutical PreparationsIBA
06/2022 - 04/2004
5Metformin (Glucophage)FDA LinkGeneric
02/2022 - 07/2011
5CytochromesIBA
01/2022 - 04/2013
5Sunitinib (Sutent)FDA Link
01/2017 - 05/2013
5LigandsIBA
04/2015 - 09/2004
4CateninsIBA
06/2022 - 01/2017
4Heavy MetalsIBA
02/2017 - 09/2004
4AntioxidantsIBA
11/2016 - 02/2011
4Polychlorinated Dibenzodioxins (TCDD)IBA
01/2012 - 09/2004
4Oxidoreductases (Dehydrogenase)IBA
01/2012 - 04/2004
3LeptinIBA
03/2022 - 01/2020
3AdiponectinIBA
03/2022 - 01/2020
3Gefitinib (Iressa)FDA Link
01/2020 - 01/2014
3CytokinesIBA
05/2016 - 04/2015
3Ketoconazole (Nizoral)FDA LinkGeneric
03/2016 - 05/2007
3CarrageenanIBA
11/2015 - 02/2015
3Reactive Oxygen Species (Oxygen Radicals)IBA
01/2013 - 09/2006
3Glutathione Transferase (Glutathione S-Transferase)IBA
01/2012 - 09/2004
3NAD (NADH)IBA
01/2012 - 09/2004
3quinone (benzoquinone)IBA
01/2012 - 09/2004
2lead nitrateIBA
09/2022 - 09/2022
2AdipokinesIBA
03/2022 - 01/2021
2Polycyclic Aromatic Hydrocarbons (Polynuclear Aromatic Hydrocarbons)IBA
01/2022 - 01/2006
2anthraceneIBA
12/2021 - 04/2015
2Transcription Factors (Transcription Factor)IBA
03/2020 - 04/2014
2CreatinineIBA
08/2019 - 03/2015
2Urea (Carbamide)FDA LinkGeneric
08/2019 - 03/2015
2SmokeIBA
02/2019 - 01/2012
2CatalaseIBA
11/2016 - 03/2015
2Caspase 3 (Caspase-3)IBA
11/2016 - 06/2016
2LipopolysaccharidesIBA
05/2016 - 01/2015
2CarcinogensIBA
04/2015 - 12/2007
2ResveratrolIBA
03/2014 - 04/2013
2SB 203580IBA
03/2014 - 09/2011
2Creatine Kinase (Creatine Phosphokinase)IBA
04/2013 - 04/2013
2CopperIBA
02/2008 - 09/2004
2MercuryIBA
02/2008 - 09/2004
2AzolesIBA
12/2007 - 05/2007
2Itraconazole (Sporanox)FDA LinkGeneric
12/2007 - 05/2007
2beta-NaphthoflavoneIBA
11/2004 - 09/2004
2MethylcholanthreneIBA
11/2004 - 09/2004
2Benzo(a)pyreneIBA
11/2004 - 09/2004
1NF-kappa B (NF-kB)IBA
09/2022
1XenobioticsIBA
06/2022
1Polylactic Acid-Polyglycolic Acid CopolymerIBA
06/2022
1ponatinibIBA
06/2022
1polyethylene glycol-poly(lactide-co-glycolide)IBA
06/2022
1Actins (F Actin)IBA
03/2022
1Immune Checkpoint InhibitorsIBA
02/2022
1Environmental Pollutants (Pollutants, Environmental)IBA
08/2021
1Leucine (L-Leucine)FDA Link
01/2020
1Hormones (Hormone)IBA
01/2020
1Biomarkers (Surrogate Marker)IBA
01/2020
1ErbB Receptors (EGF Receptor)IBA
01/2020
1venetoclaxIBA
01/2020
1Sorafenib (BAY 43-9006)FDA Link
10/2019
1PhloretinIBA
10/2019

Therapy/Procedure

4Therapeutics
12/2021 - 01/2014